Question 26 of 46

Yes, that is correct.

Esters are biotransformed primarily in the plasma. They are hydrolyzed by the enzyme pseudocholinesterase.

There is concern in patients with an atypical form of pseudocholinesterase, found in 1 out of every 2,800 people. These individuals cannot hydrolyze esters and consequently administeration of an ester to these patients will result in higher blood levels of the ester for a longer period of time with an increased potential for toxicity.